Description: Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Author(s): Caroline Fonta, Laszlo Negyessy Format: Paperback Publisher: Springer, Netherlands Imprint: Springer ISBN-13: 9789402402735, 978-9402402735 Synopsis Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of TNAP activity is a lethal condition. Recent findings of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral cortex indicates that in addition to its metabolic and skeletal functions, TNAP also plays a role in regulating cerebral functions, most probably cognition. In fact, TNAP disturbance could result in complex diseases such as epilepsy, developmental retardation and Alzheimer's disease. Available data suggest that, regarding brain functions, TNAP is a potentially important target of clinical research. This book aims to provide an overview of our current understanding of the functions of TNAP in the brain and on other tissues and organs.
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Book Title: Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)
Item Height: 235 mm
Item Width: 155 mm
Series: Subcellular Biochemistry
Author: Laszlo Negyessy, Caroline Fonta
Publication Name: Neuronal Tissue-Nonspecific Alkaline Phosphatase (Tnap)
Format: Paperback
Language: English
Publisher: Springer
Subject: Zoology, Biology, Psychiatry
Publication Year: 2016
Type: Textbook
Item Weight: 7086 g
Number of Pages: 395 Pages
