Description: Mathematical Modelling of Chromosome Replication and Replicative Stress by Jens Karschau Estimated delivery 3-12 business days Format Hardcover Condition Brand New Description DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism of its replication remains rather elusive.This work makes important contributions to this line of research. In particular, it addresses two key questions in the area of DNA replication: which evolutionary forces drive the positioning of replication origins in the chromosome and how is the spatial organization of replication factories achieved inside the nucleus of a cell?.A cross-disciplinary approach uniting physics and biology is at the heart of this research. Along with experimental support, statistical physics theory produces optimal origin positions and provides a model for replication fork assembly in yeast. Advances made here can potentially further our understanding of disease mechanisms such as the abnormal replication in cancer. Publisher Description DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism of its replication remains rather elusive.This work makes important contributions to this line of research. In particular, it addresses two key questions in the area of DNA replication: which evolutionary forces drive the positioning of replication origins in the chromosome and how is the spatial organization of replication factories achieved inside the nucleus of a cell?.A cross-disciplinary approach uniting physics and biology is at the heart of this research. Along with experimental support, statistical physics theory produces optimal origin positions and provides a model for replication fork assembly in yeast. Advances made here can potentially further our understanding of disease mechanisms such as the abnormal replication in cancer. Details ISBN 3319088602 ISBN-13 9783319088600 Title Mathematical Modelling of Chromosome Replication and Replicative Stress Author Jens Karschau Format Hardcover Year 2014 Pages 76 Edition 2015th Publisher Springer International Publishing AG GE_Item_ID:137672196; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys
Price: 139.5 USD
Location: Fairfield, Ohio
End Time: 2024-12-01T03:16:13.000Z
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ISBN-13: 9783319088600
Book Title: Mathematical Modelling of Chromosome Replication and Replicative
Number of Pages: Xiii, 76 Pages
Publication Name: Mathematical Modelling of Chromosome Replication and Replicative Stress
Language: English
Publisher: Springer International Publishing A&G
Publication Year: 2014
Subject: Materials Science / General, Life Sciences / Biophysics, Life Sciences / Genetics & Genomics, System Theory, Physics / Mathematical & Computational
Item Weight: 11.3 Oz
Type: Textbook
Item Length: 9.3 in
Author: Jens Karschau
Subject Area: Technology & Engineering, Science
Item Width: 6.1 in
Series: Springer Theses Ser.
Format: Hardcover
