Mass Spectrometry Imaging of Small Molecules (Methods in Molecular Biology)

Description: Mass Spectroscopy Imaging (MSI) has emerged as an enabling technique to provide insight into the molecular entities within cells, tissues and whole-body samples and to understand inherent complexities within biological metabolomes. In Mass Spectrometry Imaging of Small Molecules: Methods and Protocols, experts in the MSI field present techniques for 2D and 3D visualization and quantification of a wide array of small molecular species present in biologically relevant samples. Chapters provide detailed operational instructions from sample preparation to method selection, from comparative quantification to structural identification and from data collection to visualization of small molecule mapping in complex samples. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry Imaging of Small Molecules: Methods and Protocols aims to bring the rapidly maturing methods of metabolic imaging to life science researchers and to minimize technical intimidation in adapting new technological platforms in biological research. 1. Current Status and Future Prospects of Mass Spectrometry Imaging of Small Molecules Victoria L. Brown and Lin He 2. Sample Preparation for 3D SIMS Chemical Imaging of Cells Nicholas Winograd and Anna Bloom 3. TOF-SIMS Imaging of Lipids on Rat Brain Sections David Touboul and Alain Brunelle 4. MALDI-MS Assisted Molecular Imaging of Metabolites in Legume Plants Erin Gemperline and Lingjun Li 5. MALDI Mass Spectrometry Imaging of Lipids and Primary Metabolites on Rat Brain Sections David Touboul and Alain Brunelle 6. Multiplex MALDI-MS Imaging of Plant Metabolites Using a Hybrid MS System Andrew R. Korte, Gargey B. Yagnik, Adam D. Feenstra, and Young Jin Lee 7. DESI Imaging of Small Molecules in Biological Tissues Elaine C. Cabral and Demian R. Ifa 8. Desorption Electrospray Ionization Imaging of Small Organics on Mineral Surfaces Rachel V. Bennett and Facundo M. Fernández 9. Imaging of Plant Materials Using Indirect Desorption Electrospray Ionization Mass Spectrometry Christian Janfelt 10. Imaging of Lipids and Metabolites Using Nanospray Desorption Electrospray Ionization Mass Spectrometry Ingela Lanekoff and Julia Laskin 11. Electrospray Laser Desorption Ionization (ELDI) Mass Spectrometry for Molecular Imaging of Small Molecules on Tissues Min-Zong Huang, Siou-Sian Jhang, and Jentaie Shiea 12. Automated Cell-By-Cell Tissue Imaging and Single Cell Analysis for Targeted Morphologies by Laser Ablation Electrospray Ionization Mass Spectrometry Hang Li, Brian K. Smith, Bindesh Shrestha, Lászlo Márk, and Akos Vertes 13. Laser Ablation Sample Transfer for Mass Spectrometry Imaging Sung-Gun Park and Kermit K. Murray 14. Nanostructure-Based Mass Spectrometry: High Sensitivity, Enzyme Activity Analysis and Metabolite Imaging Michael E. Kurczy, Trent R. Northen, Sunia A. Trauger, and Gary Siuzdak 15. Nanostructure-Initiator Mass Spectrometry (NIMS) for Molecular Mapping of Animal Tissues Tara N. Moening, Victoria L. Brown, and Lin He 16. Nanoparticle-Assisted Laser Desorption/Ionization for Metabolite Imaging Michihiko Waki, Eiji Sugiyama, Takeshi Kondo, Keigo Sano, and Mitsutoshi Setou 17. Matrix-Enhanced Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (ME-SALDI-MS) for Mass Spectrometry Imaging of Small Molecules Victoria L. Brown, Qiang Liu, and Lin He 18. Laser Desorption Postionization Mass Spectrometry Imaging of Biological Targets Artem Akhmetov, Chhavi Bhardwaj, and Luke Hanley 19. Data Processing and Analysis for Mass Spectrometry Imaging Jiangjian Liu, Xingchuang Xiong, and Zheng Ouyang.

Price: 153 AUD

Location: Hillsdale, NSW

End Time: 2024-12-09T13:39:14.000Z

Shipping Cost: 31.24 AUD